GSH IS CRITICAL IN MANY CELLULAR REACTIONS

1. GSH reacts with various physiological metabolites such as, estrogen, prostaglandins, leukotrienes, and chemicals, such as bromobenzene and counteracts acetaminophen overdose
2. GSH interacts with Nitric oxide and both have critical roles regulating lipids, glucose, and amino acid utilization
3. GSH is involved with the removal of the carcinogen, Formaldehyde, from the body
4. GSH is required for the prostaglandin H2 pathways
5. GSH inhibits Influenza virus infection
6. GSH is involved in many other important metabolic pathways, including protein metabolism
7. GSH is required for the proliferation of cells, including lymphocytes and intestinal epithelial cells
8. GSH plays an important role in spermatogenesis and sperm maturation
9. GSH is essential for the activation of T-lymphocytes and polymorphonuclear leukocytes, and is required for cytokine production. GSH is important for successful immune responses when the host is immunologically challenged
10. GSH is involved in the process of maintaining Vitamin C and E in the active metabolic forms

Literature Cited

1. Ballatori et al (2009) Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009 March; 390(3): 191–214.
2. Sies, H. (1999) Glutathione and its cellular functions. Free Radic. Biol. Med. 27:916-921.
3. Guoyao Wu2, Yun-Zhong Fang, Sheng Yang, Joanne R. Lupton, and Nancy D. Turner. (2004) Glutathione Metabolism and Its Implications for Health. Am. Soc. Nut. Sci.
4. Townsend, D. M., Tew, K. D. & Tapiero, H. (2003) The importance of glutathione in human disease. Biomed. Pharmacother. 57:145-155.
5. Badaloo, A., Reid, M., Forrester, T., Heird, W. C. & Jahoor, F. (2002) Cysteine supplementation improves the erythrocyte glutathione synthesis rate in children with severe edematous malnutrition. Glutathione Metabolism and Its Implications for Health.Am. J. Clin. Nutr. 76:646-652.
6. Jones, D. P. (2002) Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol. 348:93-112.
7. Lyons, J., Rauh-Pfeiffer, A., Yu, Y. M., Lu, X. M., Zurakowski, D., Tompkins, R. G., Ajami, A. M., Young, V. R. & Castillo, L. (2000) Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. Proc. Natl. Acad. Sci. U.S.A. 97:5071-5076.
8. Yu, Y. M., Ryan, C. M., Fei, Z. W., Lu, X. M., Castillo, L., Schultz, J. T., Tompkins, R. G. & Young, V. R. (2002) Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans. Am. J. Physiol. 282:E247-E258.
9. Lu, S. C. (2000) Regulation of glutathione synthesis. Curr. Top. Cell Regul. 36:95-116.
10. Griffith, O. W. (1999) Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic. Biol. Med. 27:922-935.
11. Canals, S., Casarejos, M. J., de Bernardo, S., Rodriguez-Martin, E. & Mena, M. A. (2003) Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase. J. Biol. Chem. 278:21542-21549.
12. Johnson, A. T., Kaufmann, Y. C., Luo, S., Todorova, V. & Klimberg, V. S. (2003) Effect of glutamine on glutathione, IGF-1, and TGF-β1. J. Surg. Res. 111:222-228.
13. Fang, Y. Z., Yang, S. & Wu, G. (2002) Free radicals, antioxidants, and nutrition. Nutrition 18:872-879.
14. Lei, X. G. (2002) In vivo antioxidant role of glutathione peroxidase: evidence from knockout mice. Methods Enzymol. 347:213-225.
15. Cai, J., Chen, Y., Seth, S., Furukawa, S., Compans, R. W. & Jones, D. P. (2003) Inhibition of influenza infection by glutathione. Free Radic. Biol. Med. 34:928-936.

Standard Dose

• Take 6 sprays by mouth, twice daily.

Higher Dose

• Take 12 sprays by mouth, twice daily.

Optimal Use

• Spray and swallow. You may take other Results RNA formulas immediately.
• Do not eat or drink for 2 minutes following.
• Take as recommended by your physician.
• Take twice daily to maintain optimal health.

Ultra-Pure Deionized Water, S-Acetyl-L-Glutathione, N-Acetyl L-Cysteine (NAC), Acetyl L-Carnitine, L-Glutamine, L-Glutathione Tripeptides (Reduced), Lipoic Acid (R-Fraction), TMG (trimethylglycine).

Other Ingredients: Organic Peppermint (leaves) (Mentha x piperita), Ag

Take ACG Glutathione Extra Strength with the Total Body Detox System Extra Strength to provide additional support for natural detoxification.

Or purchase together in the Ultimate Body Detox System.

• Advanced Cellular Technology – delivers the power of each ingredient in the most effective manner; promotes rapid absorption
• Absence of side effects – no GI discomfort
• Intra-oral spray delivery – high patient compliance
• Maintenance application – can be taken daily for prophylaxis and support

ACG Glutathione Extra Strength is produced under strict cGMP FDA guidelines for the manufacturing of dietary supplements. For purity and quality, ACG Glutathione Extra Strength contains no preservatives • no alcohol • no artificial coloring. For customer support, please call +1 (630) 216 – 4933